منابع مشابه
Ouabain binding and cation transport in human erythrocytes.
In the present studies we have explored the relation between ouabain binding and the inhibition of potassium influx in intact human erythrocytes. The rate at which bound ouabain molecules dissociate from the erythrocyte membrane is not altered by complete replacement of choline with sodium or by partial replacement with potassium. These findings indicate that the effects of these cations on oua...
متن کاملCation Exchange in Mammalian Erythrocytes
Freshly drawn heparinized human whole blood is exposed to x-rays in amounts up to 54,000 r in vitro and then equilibrated under a controlled atmosphere at 24 or 38 degrees C. For as long as 26 hours following exposure, potassium is progressively lost from the cells and quantitatively replaced by sodium with little, if any, osmotic disturbance. The mean rate of loss at 20,000 r and 24 degrees C....
متن کاملMetabolic activation of styrene by erythrocytes detected as increased sister chromatid exchanges in cultured human lymphocytes.
Styrene induces sister chromatid exchanges (SCEs) in human whole-blood lymphocyte cultures without exogenous metabolizing systems, which indicates that styrene is metabolically activated in this in vitro system. Whole-blood lymphocyte cultures from 11 male donors showed a clear increase in SCEs after a 48-hr treatment with styrene (2 mM) or with the reactive metabolite styrene 7,8-oxide (0.15 m...
متن کاملEffects of ribosides and related compounds on cation transport in cold-stored human erythrocytes.
I. A Fluorometric 1 1ethod for the Measurement of 4-amino-lO-methyl Pteroylglutamic Acid (Amethopterin) in Plasma. M. V. Freeman.... 1 II. Effects of Ribosides and Related Compounds on Cation Transport in ColdStored Human Erythrocytes. J. B. Kahn, Jr. and Shelby B. Cohen.... 9 III. Effects of LSD 25, BOL 148, Bufotenine, Mescaline and Ibogaine on the Potentiation of Hexobarbital Hypnosis Produc...
متن کاملEffect of Protein Kinase C Activation on Cytoskeleton and Cation Transport in Human Erythrocytes
Certain manifestations of alterations of membrane cytoskeleton, protein kinase C activity, and ion transport were revealed in erythrocytes of patients with essential hypertension: 1) the average volume of erythrocytes is reduced by 4%; 2) about 7% of the total number of erythrocytes is represented by cup-shaped forms compared with 1.5 to 3.0% in the control group; 3) basal phospborylation of Ba...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1959
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1959.sp006168